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148
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BMCBI
2007
15 years 3 months ago
2007
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
133
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BMCBI
2010
15 years 3 months ago
2010
Background: Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment. While these lists represent an accurat...
144
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BMCBI
2008
15 years 3 months ago
2008
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
138
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BMCBI
2008
15 years 3 months ago
2008
Background: The DNA microarray technology allows the measurement of expression levels of thousands of genes under tens/hundreds of different conditions. In microarray data, genes ...
161
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BMCBI
2008
15 years 3 months ago
2008
Background: Protein-protein interactions are ubiquitous and essential for all cellular processes. High-resolution X-ray crystallographic structures of protein complexes can reveal...