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» A Permutation Approach to Validation
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118
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BMCBI
2007
99views more  BMCBI 2007»
15 years 3 months ago
The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data
Background: The combination of mass spectrometry and solution phase amide hydrogen/deuterium exchange (H/D exchange) experiments is an effective method for characterizing protein ...
B. D. Pascal, M. J. Chalmers, S. A. Busby, C. C. M...
122
Voted
BMCBI
2010
114views more  BMCBI 2010»
15 years 3 months ago
Detecting variants with Metabolic Design, a new software tool to design probes for explorative functional DNA microarray develop
Background: Microorganisms display vast diversity, and each one has its own set of genes, cell components and metabolic reactions. To assess their huge unexploited metabolic poten...
Sébastien Terrat, Eric Peyretaillade, Olivi...
108
Voted
BMCBI
2007
126views more  BMCBI 2007»
15 years 3 months ago
Reconstruction of cell population dynamics using CFSE
Background: Quantifying cell division and death is central to many studies in the biological sciences. The fluorescent dye CFSE allows the tracking of cell division in vitro and i...
Andrew Yates, Cliburn Chan, Jessica Strid, Simon M...
141
Voted
BMCBI
2010
133views more  BMCBI 2010»
15 years 3 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
149
Voted
BMCBI
2010
243views more  BMCBI 2010»
15 years 3 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...