73 search results - page 4 / 15 » A Practical Approach to Significance Assessment in Alignment... |
BMCBI
2010
13 years 8 months ago
2010
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
ESWS
2008
Springer
13 years 9 months ago
2008
Springer
Evaluation of ontology alignments is in practice done in two ways: (1) assessing individual correspondences and (2) comparing the alignment to a reference alignment. However, this ...
BMCBI
2008
13 years 8 months ago
2008
Background: We propose a multiple sequence alignment (MSA) algorithm and compare the alignment-quality and execution-time of the proposed algorithm with that of existing algorithm...
BMCBI
2007
13 years 8 months ago
2007
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
ALMOB
2007
13 years 8 months ago
2007
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...