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143
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BMCBI
2010
15 years 4 months ago
2010
Background: Mass spectrometry (MS) is an essential analytical tool in proteomics. Many existing algorithms for peptide detection are based on isotope template matching and usually...
145
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BMCBI
2007
15 years 4 months ago
2007
Background: Sequence motifs representing transcription factor binding sites (TFBS) are commonly encoded as position frequency matrices (PFM) or degenerate consensus sequences (CS)...
158
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BMCBI
2007
15 years 4 months ago
2007
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
107
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BMCBI
2007
15 years 4 months ago
2007
Background: Orthology is one of the cornerstones of gene function prediction. Dividing the phylogenetic relations between genes into either orthologs or paralogs is however an ove...
135
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BMCBI
2007
15 years 4 months ago
2007
Background: In many laboratory-based high throughput microarray experiments, there are very few replicates of gene expression levels. Thus, estimates of gene variances are inaccur...