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» A Protein Family Classification Method for Analysis of Large...
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BMCBI
2004
208views more  BMCBI 2004»
13 years 7 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
BMCBI
2004
123views more  BMCBI 2004»
13 years 7 months ago
Interaction profile-based protein classification of death domain
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
Drew Lett, Michael Hsing, Frederic Pio
BMCBI
2006
92views more  BMCBI 2006»
13 years 7 months ago
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
Anne-Kathrin Schultz, Ming Zhang, Thomas Leitner, ...
BMCBI
2004
167views more  BMCBI 2004»
13 years 7 months ago
Feature selection for splice site prediction: A new method using EDA-based feature ranking
Background: The identification of relevant biological features in large and complex datasets is an important step towards gaining insight in the processes underlying the data. Oth...
Yvan Saeys, Sven Degroeve, Dirk Aeyels, Pierre Rou...
BMCBI
2006
91views more  BMCBI 2006»
13 years 7 months ago
In silico identification of putative promoter motifs of White Spot Syndrome Virus
Background: White Spot Syndrome Virus, a member of the virus family Nimaviridae, is a large dsDNA virus infecting shrimp and other crustacean species. Although limited information...
Hendrik Marks, Xin-Ying Ren, Hans Sandbrink, Mari&...