800 search results - page 111 / 160 » A Repulsive Clustering Algorithm for Gene Expression Data |
WABI
2010
Springer
13 years 6 months ago
2010
Springer
In this paper we present a novel expectation-maximization algorithm for inference of alternative splicing isoform frequencies from high-throughput transcriptome sequencing (RNA-Seq...
COCOON
2005
Springer
14 years 1 months ago
2005
Springer
In computational biology, gene order data is often modelled as signed permutations. A classical problem in genome comparison is to detect conserved segments in a permutation, that ...
BMCBI
2004
13 years 7 months ago
2004
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
BMCBI
2007
13 years 7 months ago
2007
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
BMCBI
2007
13 years 7 months ago
2007
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...