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ISMB
2001
13 years 8 months ago
Molecular classification of multiple tumor types
Using gene expression data to classify tumor types is a very promising tool in cancer diagnosis. Previous works show several pairs of tumor types can be successfully distinguished...
Chen-Hsiang Yeang, Sridhar Ramaswamy, Pablo Tamayo...
BMCBI
2010
84views more  BMCBI 2010»
13 years 7 months ago
Testing the additional predictive value of high-dimensional molecular data
Background: While high-dimensional molecular data such as microarray gene expression data have been used for disease outcome prediction or diagnosis purposes for about ten years i...
Anne-Laure Boulesteix, Torsten Hothorn
BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
COMPLIFE
2005
Springer
14 years 27 days ago
Robust Perron Cluster Analysis for Various Applications in Computational Life Science
In the present paper we explain the basic ideas of Robust Perron Cluster Analysis (PCCA+) and exemplify the different application areas of this new and powerful method. Recently, ...
Marcus Weber, Susanna Kube
BMCBI
2007
127views more  BMCBI 2007»
13 years 7 months ago
Characterization of protein-interaction networks in tumors
Background: Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the functional cellular status. PINs can be for...
Alexander Platzer, Paul Perco, Arno Lukas, Bernd M...