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BMCBI
2007
140views more  BMCBI 2007»
13 years 7 months ago
Prediction potential of candidate biomarker sets identified and validated on gene expression data from multiple datasets
Background: Independently derived expression profiles of the same biological condition often have few genes in common. In this study, we created populations of expression profiles...
Michael Gormley, William Dampier, Adam Ertel, Bilg...
BMCBI
2005
141views more  BMCBI 2005»
13 years 7 months ago
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
Nils E. Magnusson, Alessandra K. Cardozo, Mogens K...
ACIIDS
2010
IEEE
171views Database» more  ACIIDS 2010»
13 years 10 months ago
Evolving Concurrent Petri Net Models of Epistasis
Abstract. A genetic algorithm is used to learn a non-deterministic Petri netbased model of non-linear gene interactions, or statistical epistasis. Petri nets are computational mode...
Michael Mayo, Lorenzo Beretta
BMCBI
2010
97views more  BMCBI 2010»
13 years 7 months ago
Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
Background: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on es...
Dirk Repsilber, Sabine Kern, Anna Telaar, Gerhard ...
ML
2010
ACM
185views Machine Learning» more  ML 2010»
13 years 2 months ago
Learning to rank on graphs
Graph representations of data are increasingly common. Such representations arise in a variety of applications, including computational biology, social network analysis, web applic...
Shivani Agarwal