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» A Sequence Alignment Model Based on the Averaged Perceptron
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NAR
1998
86views more  NAR 1998»
13 years 7 months ago
Pfam: multiple sequence alignments and HMM-profiles of protein domains
Pfam contains multiple alignments and hidden Markov model based profiles (HMM-profiles) of complete protein domains. The definition of domain boundaries, family members and alignm...
Erik L. L. Sonnhammer, Sean R. Eddy, Ewan Birney, ...
BMCBI
2010
64views more  BMCBI 2010»
13 years 8 months ago
State of the art: refinement of multiple sequence alignments
Correction to Chakrabarti S, Lanczycki CJ, Panchenko AR, Przytycka TM, Thiessen PA and Bryant SH: State of the art: refinement of multiple sequence alignments. BMC Bioinformatics ...
Saikat Chakrabarti, Christopher J. Lanczycki, Anna...
ALMOB
2008
85views more  ALMOB 2008»
13 years 8 months ago
Noisy: Identification of problematic columns in multiple sequence alignments
Motivation: Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data are notoriously plagued by two effects: homoplasies and alignment errors. Larg...
Andreas W. M. Dress, Christoph Flamm, Guido Fritzs...
CPM
2004
Springer
156views Combinatorics» more  CPM 2004»
14 years 1 months ago
A Computational Model for RNA Multiple Structural Alignment.
Abstract. This paper addresses the problem of aligning multiple sequences of non-coding RNA genes. We approach this problem with the biologically motivated paradigm that scoring of...
Eugene Davydov, Serafim Batzoglou
RECOMB
1997
Springer
14 years 2 days ago
Sequence alignment with tandem duplication
Algorithm development for comparing and aligning biological sequences has, until recently, been based on the SI model of mutational events which assumes that modi cation of sequen...
Gary Benson