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ISMDA
2005
Springer
14 years 1 months ago
Extracting Molecular Diversity Between Populations Through Sequence Alignments
The use of sequence alignments for establishing protein homology relationships has an extensive tradition in the field of bioinformatics, and there is an increasing desire for more...
Steinar Thorvaldsen, Tor Flå, Nils Willassen
ALMOB
2006
80views more  ALMOB 2006»
13 years 7 months ago
Pattern statistics on Markov chains and sensitivity to parameter estimation
Background: In order to compute pattern statistics in computational biology a Markov model is commonly used to take into account the sequence composition. Usually its parameter mu...
Grégory Nuel
WABI
2001
Springer
162views Bioinformatics» more  WABI 2001»
14 years 3 days ago
A Simple Hyper-Geometric Approach for Discovering Putative Transcription Factor Binding Sites
A central issue in molecular biology is understanding the regulatory mechanisms that control gene expression. The recent flood of genomic and postgenomic data opens the way for co...
Yoseph Barash, Gill Bejerano, Nir Friedman
CIBCB
2007
IEEE
14 years 2 months ago
Overestimation for Multiple Sequence Alignment
Abstract— Multiple sequence alignment is an important problem in computational biology. A-star is an algorithm that can be used to find exact alignments. We present a simple mod...
Tristan Cazenave
RECOMB
2006
Springer
14 years 8 months ago
Simple and Fast Inverse Alignment
For as long as biologists have been computing alignments of sequences, the question of what values to use for scoring substitutions and gaps has persisted. While some choices for s...
John D. Kececioglu, Eagu Kim