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GCB
2005
Springer
98views Biometrics» more  GCB 2005»
14 years 28 days ago
Composite Module Analyst: A Fitness-Based Tool for Prediction of Transcription Regulation
: Functionally related genes involved in the same molecular-genetic, biochemical, or physiological process are often regulated coordinately Such regulation is provided by precisely...
Alexander E. Kel, Tatiana Konovalova, Tagir Valeev...
BICOB
2009
Springer
14 years 2 days ago
Computational Prediction of Genes Translationally Regulated by Cytoplasmic Polyadenylation Elements
Cytoplasmic post-transcriptional modification of mRNA transcripts in the form of polyadenylated (poly(A)) tails plays a key role in their translational control. The timing and degr...
Eric C. Rouchka, Xiangping Wang, James H. Graham, ...
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Bounded search for de novo identification of degenerate cis-regulatory elements
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
Jonathan M. Carlson, Arijit Chakravarty, Radhika S...
BMCBI
2008
82views more  BMCBI 2008»
13 years 7 months ago
Studying the functional conservation of cis-regulatory modules and their transcriptional output
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...
Denis C. Bauer, Timothy L. Bailey
BIBE
2007
IEEE
129views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Statistial Analysis of nucleosome occupancy and histone modification data
Abstract-- In eukaryotic cells, genomic DNAs wrap around beadlike molecules, called nucleosomes, so as to pack more compactly in the nucleus of the cell. The nucleosome is made up ...
Guo-Cheng Yuan, Jun S. Liu