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BMCBI
2006
115views more  BMCBI 2006»
13 years 10 months ago
SimArray: a user-friendly and user-configurable microarray design tool
Background: Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Rega...
Richard P. Auburn, Roslin R. Russell, Bettina Fisc...
BMCBI
2006
99views more  BMCBI 2006»
13 years 10 months ago
A proposed metric for assessing the measurement quality of individual microarrays
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
Kyoungmi Kim, Grier P. Page, T. Mark Beasley, Step...
BMCBI
2007
138views more  BMCBI 2007»
13 years 9 months ago
A novel Bayesian approach to quantify clinical variables and to determine their spectroscopic counterparts in 1H NMR metabonomic
Background: A key challenge in metabonomics is to uncover quantitative associations between multidimensional spectroscopic data and biochemical measures used for disease risk asse...
Aki Vehtari, Ville-Petteri Mäkinen, Pasi Soin...
JCB
2006
185views more  JCB 2006»
13 years 9 months ago
A Probabilistic Methodology for Integrating Knowledge and Experiments on Biological Networks
Biological systems are traditionally studied by focusing on a specific subsystem, building an intuitive model for it, and refining the model using results from carefully designed ...
Irit Gat-Viks, Amos Tanay, Daniela Raijman, Ron Sh...
TIP
2002
131views more  TIP 2002»
13 years 9 months ago
Optimal edge-based shape detection
Abstract--We propose an approach to accurately detecting twodimensional (2-D) shapes. The cross section of the shape boundary is modeled as a step function. We first derive a one-d...
Hankyu Moon, Rama Chellappa, Azriel Rosenfeld