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» A Theoretical Analysis of Gene Selection
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BMCBI
2010
100views more  BMCBI 2010»
13 years 9 months ago
Trimming of mammalian transcriptional networks using network component analysis
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Linh M. Tran, Daniel R. Hyduke, James C. Liao
BMCBI
2007
135views more  BMCBI 2007»
13 years 9 months ago
Detecting multivariate differentially expressed genes
Background: Gene expression is governed by complex networks, and differences in expression patterns between distinct biological conditions may therefore be complex and multivariat...
Roland Nilsson, José M. Peña, Johan ...
GECCO
2008
Springer
118views Optimization» more  GECCO 2008»
13 years 10 months ago
An analysis of multi-sampled issue and no-replacement tournament selection
Standard tournament selection samples individuals with replacement. The sampling-with-replacement strategy has its advantages but also has issues. One of the commonly recognised i...
Huayang Xie, Mengjie Zhang, Peter Andreae, Mark Jo...
BMCBI
2008
124views more  BMCBI 2008»
13 years 9 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li
BMCBI
2007
207views more  BMCBI 2007»
13 years 9 months ago
Analyzing in situ gene expression in the mouse brain with image registration, feature extraction and block clustering
Background: Many important high throughput projects use in situ hybridization and may require the analysis of images of spatial cross sections of organisms taken with cellular lev...
Manjunatha Jagalur, Chris Pal, Erik G. Learned-Mil...