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BMCBI
2010
132views more  BMCBI 2010»
13 years 8 months ago
New statistical potential for quality assessment of protein models and a survey of energy functions
Background: Scoring functions, such as molecular mechanic forcefields and statistical potentials are fundamentally important tools in protein structure modeling and quality assess...
Dmitry Rykunov, András Fiser
BMCBI
2008
106views more  BMCBI 2008»
13 years 8 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
BMCBI
2006
120views more  BMCBI 2006»
13 years 8 months ago
SCOWLP: a web-based database for detailed characterization and visualization of protein interfaces
Background: Currently there is a strong need for methods that help to obtain an accurate description of protein interfaces in order to be able to understand the principles that go...
Joan Teyra, Andreas Doms, Michael Schroeder, M. Te...
BMCBI
2007
107views more  BMCBI 2007»
13 years 8 months ago
Linking microarray reporters with protein functions
Background: The analysis of microarray experiments requires accurate and up-to-date functional annotation of the microarray reporters to optimize the interpretation of the biologi...
Stan Gaj, Arie van Erk, Rachel I. M. van Haaften, ...
JUCS
2008
210views more  JUCS 2008»
13 years 8 months ago
Systematic Characterisation of Objects in Digital Preservation: The eXtensible Characterisation Languages
: During the last decades, digital objects have become the primary medium to create, shape, and exchange information. However, in contrast to analog objects such as books that dire...
Christoph Becker, Andreas Rauber, Volker Heydegger...