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» A benchmark for Affymetrix GeneChip expression measures
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BMCBI
2007
160views more  BMCBI 2007»
13 years 7 months ago
Establishing a major cause of discrepancy in the calibration of Affymetrix GeneChips
Background: Affymetrix GeneChips are a popular platform for performing whole-genome experiments on the transcriptome. There are a range of different calibration steps, and users a...
Andrew P. Harrison, Caroline E. Johnston, Christin...
TCBB
2010
96views more  TCBB 2010»
13 years 2 months ago
A Survey of Spatial Defects in Homo Sapiens Affymetrix GeneChips
Modern biology has moved from a science of individual measurements to a science where data are collected on an industrial scale. Foremost, among the new tools for biochemistry are ...
William B. Langdon, Graham J. G. Upton, Renata da ...
BMCBI
2007
110views more  BMCBI 2007»
13 years 7 months ago
Interpretation of multiple probe sets mapping to the same gene in Affymetrix GeneChips
Background: Affymetrix GeneChip technology enables the parallel observations of tens of thousands of genes. It is important that the probe set annotations are reliable so that bio...
Maria A. Stalteri, Andrew P. Harrison
BMCBI
2006
93views more  BMCBI 2006»
13 years 7 months ago
A summarization approach for Affymetrix GeneChip data using a reference training set from a large, biologically diverse database
Background: Many of the most popular pre-processing methods for Affymetrix expression arrays, such as RMA, gcRMA, and PLIER, simultaneously analyze data across a set of predetermi...
Simon Katz, Rafael A. Irizarry, Xue Lin, Mark Trip...
ACMSE
2006
ACM
14 years 1 months ago
Automatic quality assessment of Affymetrix GeneChip data
Computing reliable gene expression levels from microarray experiments is a sophisticated process with many potential pitfalls. Quality control is one of the most important steps i...
Steffen Heber, Beate Sick