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» A branch-and-cut algorithm for multiple sequence alignment
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BMCBI
2005
152views more  BMCBI 2005»
13 years 7 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
WABI
2007
Springer
14 years 1 months ago
Shotgun Protein Sequencing
Although snake venom proteins have been proven instrumental in the design of blood clotting and cytostatic breast cancer drugs, the main method in use to sequence these unknown pr...
Pavel A. Pevzner
FPL
2010
Springer
188views Hardware» more  FPL 2010»
13 years 5 months ago
SeqHive: A Reconfigurable Computer Cluster for Genome Re-sequencing
We demonstrate how Field Programmable Gate Arrays (FPGAs) may be used to address the computing challenges associated with assembling genome sequences from recent ultra-high-through...
Kristian Stevens, Henry Chen, Terry Filiba, Peter ...
WACV
2005
IEEE
14 years 1 months ago
Simultaneous Localization and Recognition of Dynamic Hand Gestures
A method for the simultaneous localization and recognition of dynamic hand gestures is proposed. At the core of this method is a dynamic space-time warping (DSTW) algorithm, that ...
Jonathan Alon, Vassilis Athitsos, Quan Yuan, Stan ...
BMCBI
2008
145views more  BMCBI 2008»
13 years 7 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...