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BMCBI
2010
13 years 10 months ago
2010
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
BMCBI
2010
13 years 10 months ago
2010
Background: A protein binding hot spot is a small cluster of residues tightly packed at the center of the interface between two interacting proteins. Though a hot spot constitutes...
BMCBI
2010
2010
Discover Protein Complexes in Protein-Protein Interaction Networks Using Parametric Local Modularity
13 years 10 months ago
Background: Recent advances in proteomic technologies have enabled us to create detailed protein-protein interaction maps in multiple species and in both normal and diseased cells...
BMCBI
2008
13 years 10 months ago
2008
Background: Phylogenies, i.e., the evolutionary histories of groups of taxa, play a major role in representing the interrelationships among biological entities. Many software tool...
CORR
2008
Springer
13 years 10 months ago
2008
Springer
In this paper, we propose a general cross-layer optimization framework in which we explicitly consider both the heterogeneous and dynamically changing characteristics of delay-sens...