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» A cluster validity framework for genome expression data
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IDA
2007
Springer
13 years 9 months ago
An unsupervised clustering approach for leukaemia classification based on DNA micro-arrays data
: DNA micro-arrays provide thousands of genomic expressions on the same subject. A main issue is then to find the subset of genes whose degeneration is responsible of a certain typ...
Simone Garatti, Sergio Bittanti, Diego Liberati, A...
IDA
2005
Springer
14 years 3 months ago
Biological Cluster Validity Indices Based on the Gene Ontology
With the invention of biotechnological high throughput methods like DNA microarrays and the analysis of the resulting huge amounts of biological data, clustering algorithms gain ne...
Nora Speer, Christian Spieth, Andreas Zell
BMCBI
2005
122views more  BMCBI 2005»
13 years 9 months ago
GenClust: A genetic algorithm for clustering gene expression data
Background: Clustering is a key step in the analysis of gene expression data, and in fact, many classical clustering algorithms are used, or more innovative ones have been designe...
Vito Di Gesù, Raffaele Giancarlo, Giosu&egr...
BMCBI
2007
128views more  BMCBI 2007»
13 years 9 months ago
Model order selection for bio-molecular data clustering
Background: Cluster analysis has been widely applied for investigating structure in bio-molecular data. A drawback of most clustering algorithms is that they cannot automatically ...
Alberto Bertoni, Giorgio Valentini
BMCBI
2007
126views more  BMCBI 2007»
13 years 9 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...