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COOTS
1998
15 years 5 months ago
The Design and Performance of MedJava
The Java programming language has gained substantial popularity in the past two years. Java's networking features, along with the growing number of Web browsers that execute J...
Prashant Jain, Seth Widoff, Douglas C. Schmidt
128
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BMCBI
2010
116views more  BMCBI 2010»
15 years 3 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
127
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BMCBI
2010
119views more  BMCBI 2010»
15 years 3 months ago
A comparison of internal validation techniques for multifactor dimensionality reduction
Background: It is hypothesized that common, complex diseases may be due to complex interactions between genetic and environmental factors, which are difficult to detect in high-di...
Stacey J. Winham, Andrew J. Slater, Alison A. Mots...
138
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BMCBI
2008
111views more  BMCBI 2008»
15 years 3 months ago
Information-based methods for predicting gene function from systematic gene knock-downs
Background: The rapid annotation of genes on a genome-wide scale is now possible for several organisms using high-throughput RNA interference assays to knock down the expression o...
Matthew T. Weirauch, Christopher K. Wong, Alexandr...
135
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BMCBI
2007
166views more  BMCBI 2007»
15 years 3 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
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