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» A comparison of Affymetrix gene expression arrays
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BMCBI
2008
98views more  BMCBI 2008»
13 years 8 months ago
Empirical Bayes models for multiple probe type microarrays at the probe level
Background: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are...
Magnus Åstrand, Petter Mostad, Mats Rudemo
BMCBI
2007
97views more  BMCBI 2007»
13 years 8 months ago
A verification protocol for the probe sequences of Affymetrix genome arrays reveals high probe accuracy for studies in mouse, hu
Background: The Affymetrix GeneChip technology uses multiple probes per gene to measure its expression level. Individual probe signals can vary widely, which hampers proper interp...
Rudi Alberts, Peter Terpstra, Menno Hardonk, Leoni...
TCBB
2010
96views more  TCBB 2010»
13 years 3 months ago
A Survey of Spatial Defects in Homo Sapiens Affymetrix GeneChips
Modern biology has moved from a science of individual measurements to a science where data are collected on an industrial scale. Foremost, among the new tools for biochemistry are ...
William B. Langdon, Graham J. G. Upton, Renata da ...
BMCBI
2006
112views more  BMCBI 2006»
13 years 8 months ago
Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data
Background: Gene expression microarray experiments are expensive to conduct and guidelines for acceptable quality control at intermediate steps before and after the samples are hy...
Lesley Jones, Darlene R. Goldstein, Gareth P. Hugh...
BMCBI
2005
144views more  BMCBI 2005»
13 years 8 months ago
Redefinition of Affymetrix probe sets by sequence overlap with cDNA microarray probes reduces cross-platform inconsistencies in
Background: Comparison of data produced on different microarray platforms often shows surprising discordance. It is not clear whether this discrepancy is caused by noisy data or b...
Scott L. Carter, Aron C. Eklund, Brigham H. Mecham...