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» A custom FPGA for the simulation of gene regulatory networks
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CIARP
2009
Springer
14 years 2 months ago
Analysis of the GRNs Inference by Using Tsallis Entropy and a Feature Selection Approach
Abstract. An important problem in the bioinformatics field is to understand how genes are regulated and interact through gene networks. This knowledge can be helpful for many appl...
Fabrício Martins Lopes, Evaldo A. de Olivei...
BMCBI
2006
116views more  BMCBI 2006»
13 years 7 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2006
129views more  BMCBI 2006»
13 years 7 months ago
Functional clustering of yeast proteins from the protein-protein interaction network
Background: The abundant data available for protein interaction networks have not yet been fully understood. New types of analyses are needed to reveal organizational principles o...
Taner Z. Sen, Andrzej Kloczkowski, Robert L. Jerni...
BMCBI
2007
114views more  BMCBI 2007»
13 years 7 months ago
Mining and state-space modeling and verification of sub-networks from large-scale biomolecular networks
Background: Biomolecular networks dynamically respond to stimuli and implement cellular function. Understanding these dynamic changes is the key challenge for cell biologists. As ...
Xiaohua Hu, Fang-Xiang Wu
BIBE
2008
IEEE
111views Bioinformatics» more  BIBE 2008»
13 years 9 months ago
Structure learning for biomolecular pathways containing cycles
Bayesian network structure learning is a useful tool for elucidation of regulatory structures of biomolecular pathways. The approach however is limited by its acyclicity constraint...
S. Itani, Karen Sachs, Garry P. Nolan, M. A. Dahle...