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» A duplication growth model of gene expression networks
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BMCBI
2008
130views more  BMCBI 2008»
13 years 7 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...
BMCBI
2010
164views more  BMCBI 2010»
13 years 7 months ago
Gene regulatory networks modelling using a dynamic evolutionary hybrid
Background: Inference of gene regulatory networks is a key goal in the quest for understanding fundamental cellular processes and revealing underlying relations among genes. With ...
Ioannis A. Maraziotis, Andrei Dragomir, Dimitris T...
BMCBI
2010
109views more  BMCBI 2010»
13 years 7 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
CMSB
2004
Springer
13 years 11 months ago
Residual Bootstrapping and Median Filtering for Robust Estimation of Gene Networks from Microarray Data
We propose a robust estimation method of gene networks based on microarray gene expression data. It is well-known that microarray data contain a large amount of noise and some outl...
Seiya Imoto, Tomoyuki Higuchi, SunYong Kim, Euna J...
RECOMB
2009
Springer
14 years 8 months ago
Evaluating Between-Pathway Models with Expression Data
Abstract. Between-Pathway Models (BPMs) are network motifs consisting of pairs of putative redundant pathways. In this paper, we show how adding another source of high-throughput d...
Benjamin J. Hescott, Mark D. M. Leiserson, Lenore ...