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» A duplication growth model of gene expression networks
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JMLR
2006
103views more  JMLR 2006»
13 years 7 months ago
MinReg: A Scalable Algorithm for Learning Parsimonious Regulatory Networks in Yeast and Mammals
In recent years, there has been a growing interest in applying Bayesian networks and their extensions to reconstruct regulatory networks from gene expression data. Since the gene ...
Dana Pe'er, Amos Tanay, Aviv Regev
EVOW
2007
Springer
14 years 1 months ago
Bio-mimetic Evolutionary Reverse Engineering of Genetic Regulatory Networks
The effective reverse engineering of biochemical networks is one of the great challenges of systems biology. The contribution of this paper is two-fold: 1) We introduce a new meth...
Daniel Marbach, Claudio Mattiussi, Dario Floreano
CIARP
2009
Springer
14 years 2 months ago
Analysis of the GRNs Inference by Using Tsallis Entropy and a Feature Selection Approach
Abstract. An important problem in the bioinformatics field is to understand how genes are regulated and interact through gene networks. This knowledge can be helpful for many appl...
Fabrício Martins Lopes, Evaldo A. de Olivei...
BMCBI
2008
120views more  BMCBI 2008»
13 years 7 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
BMCBI
2010
118views more  BMCBI 2010»
13 years 7 months ago
svdPPCS: an effective singular value decomposition-based method for conserved and divergent co-expression gene module identifica
Background: Comparative analysis of gene expression profiling of multiple biological categories, such as different species of organisms or different kinds of tissue, promises to e...
Wensheng Zhang, Andrea Edwards, Wei Fan, Dongxiao ...