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» A duplication growth model of gene expression networks
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BMCBI
2007
136views more  BMCBI 2007»
13 years 7 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette
JMLR
2012
11 years 10 months ago
Bayesian regularization of non-homogeneous dynamic Bayesian networks by globally coupling interaction parameters
To relax the homogeneity assumption of classical dynamic Bayesian networks (DBNs), various recent studies have combined DBNs with multiple changepoint processes. The underlying as...
Marco Grzegorczyk, Dirk Husmeier
BIBM
2009
IEEE
172views Bioinformatics» more  BIBM 2009»
14 years 24 days ago
Identifying Gene Signatures from Cancer Progression Data Using Ordinal Analysis
—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
Yoon Soo Pyon, Jing Li
TCBB
2011
13 years 2 months ago
Learning Genetic Regulatory Network Connectivity from Time Series Data
Recent experimental advances facilitate the collection of time series data that indicate which genes in a cell are expressed. This paper proposes an efficient method to generate th...
Nathan A. Barker, Chris J. Myers, Hiroyuki Kuwahar...
PADS
2009
ACM
14 years 2 months ago
Scalable Time Warp on Blue Gene Supercomputers
Abstract—In this paper we illustrate scalable parallel performance for the Time Warp synchronization protocol on the L and P variants of the IBM Blue Gene supercomputer. Scalable...
David W. Bauer, Christopher D. Carothers, Akintayo...