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» A factor analysis model for functional genomics
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BMCBI
2007
146views more  BMCBI 2007»
13 years 8 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2010
216views more  BMCBI 2010»
13 years 3 months ago
Bayesian Inference of the Number of Factors in Gene-Expression Analysis: Application to Human Virus Challenge Studies
Background: Nonparametric Bayesian techniques have been developed recently to extend the sophistication of factor models, allowing one to infer the number of appropriate factors f...
Bo Chen, Minhua Chen, John William Paisley, Aimee ...
BMCBI
2008
171views more  BMCBI 2008»
13 years 8 months ago
Fuzzy association rules for biological data analysis: A case study on yeast
Background: Last years' mapping of diverse genomes has generated huge amounts of biological data which are currently dispersed through many databases. Integration of the info...
Francisco J. Lopez, Armando Blanco, Fernando Garci...
SMC
2010
IEEE
202views Control Systems» more  SMC 2010»
13 years 6 months ago
Evaluating the performance of nonnegative matrix factorization for constructing semantic spaces: Comparison to latent semantic a
—This study examines the ability of nonnegative matrix factorization (NMF) as a method for constructing semantic spaces, in which the meaning of each word is represented by a hig...
Akira Utsumi
BMCBI
2006
103views more  BMCBI 2006»
13 years 8 months ago
Cis-motifs upstream of the transcription and translation initiation sites are effectively revealed by their positional disequili
Background: The discovery of cis-regulatory motifs still remains a challenging task even though the number of sequenced genomes is constantly growing. Computational analyses using...
Kenneth W. Berendzen, Kurt Stüber, Klaus Hart...