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    BMCBI
    2008
    103views more  BMCBI 2008»
    Parameter estimation for robust HMM analysis of ChIP-chip data
    13 years 8 months ago
    Parameter estimation for robust HMM analysis of ChIP-chip data
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    Background: Tiling arrays are an important tool for the study of transcriptional activity, proteinDNA interactions and chromatin structure on a genome-wide scale at high resolutio...
    Peter Humburg, David Bulger, Glenn Stone
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    BMCBI
    2005
    122views more  BMCBI 2005»
    Quantitative analysis of EGR proteins binding to DNA: assessing additivity in both the binding site and the protein
    13 years 8 months ago
    Quantitative analysis of EGR proteins binding to DNA: assessing additivity in both the binding site and the protein
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    Background: Recognition codes for protein-DNA interactions typically assume that the interacting positions contribute additively to the binding energy. While this is known to not ...
    Jiajian Liu, Gary D. Stormo
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    ESCIENCE
    2007
    IEEE
    173views Distributed And Parallel Com...» more  ESCIENCE 2007»
    Grid-Enabling an Efficient Algorithm for Demanding Global Optimization Problems in Genetic Analysis
    13 years 12 months ago
    Grid-Enabling an Efficient Algorithm for Demanding Global Optimization Problems in Genetic Analysis
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    Abstract. We study the implementation on grid systems of an efficient algorithm for demanding global optimization problems. Specifically, we consider problems arising in the geneti...
    Mahen Jayawardena, Sverker Holmgren
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    BMCBI
    2007
    97views more  BMCBI 2007»
    In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
    13 years 8 months ago
    In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
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    Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
    Tineke Casneuf, Yves Van de Peer, Wolfgang Huber
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    BMCBI
    2011
    252views Artificial Intelligence» more  BMCBI 2011»
    A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-w
    12 years 11 months ago
    A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-w
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    Background: Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1...
    Raphael Mourad, Christine Sinoquet, Philippe Leray
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