324 search results - page 8 / 65 » A factor analysis model for functional genomics |
RECOMB
2010
Springer
14 years 2 months ago
2010
Springer
Background: The empirical frequencies of DNA k-mers in whole genome sequences provide an interesting perspective on genomic complexity, and the availability of large segments of g...
CSB
2005
IEEE
14 years 1 months ago
2005
IEEE
Functionally related genes co-evolve, probably due to the strong selection pressure in evolution. Thus we expect that they are present in multiple genomes. Physical proximity amon...
BMCBI
2007
13 years 8 months ago
2007
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
BIOCOMP
2009
13 years 5 months ago
2009
- Identification and annotation of all the functional elements in the genome, including genes and regulatory sequences, is a fundamental challenge in genomics and computational bio...
BMCBI
2005
13 years 7 months ago
2005
Background: Microarray experiments, as well as other genomic analyses, often result in large gene sets containing up to several hundred genes. The biological significance of such ...