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» A factor model to analyze heterogeneity in gene expression
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TKDE
2010
224views more  TKDE 2010»
13 years 4 months ago
Non-Negative Matrix Factorization for Semisupervised Heterogeneous Data Coclustering
Coclustering heterogeneous data has attracted extensive attention recently due to its high impact on various important applications, such us text mining, image retrieval, and bioin...
Yanhua Chen, Lijun Wang, Ming Dong
BMCBI
2007
146views more  BMCBI 2007»
13 years 10 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2004
79views more  BMCBI 2004»
13 years 9 months ago
A new mixture model approach to analyzing allelic-loss data using Bayes factors
Background: Allelic-loss studies record data on the loss of genetic material in tumor tissue relative to normal tissue at various loci along the genome. As the deletion of a tumor...
Manisha Desai, Mary J. Emond
BMCBI
2005
145views more  BMCBI 2005»
13 years 9 months ago
CAGER: classification analysis of gene expression regulation using multiple information sources
Background: Many classification approaches have been applied to analyzing transcriptional regulation of gene expressions. These methods build models that can explain a gene's...
Jianhua Ruan, Weixiong Zhang