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BMCBI
2011
12 years 10 months ago
Efficient alignment of pyrosequencing reads for re-sequencing applications
Background: Over the past few years, new massively parallel DNA sequencing technologies have emerged. These platforms generate massive amounts of data per run, greatly reducing th...
Francisco Fernandes, Paulo G. S. da Fonseca, Lu&ia...
BMCBI
2011
12 years 10 months ago
Biomarker Discovery and Redundancy Reduction towards Classification using a Multi-factorial MALDI-TOF MS T2DM Mouse Model Datase
Background: Diabetes like many diseases and biological processes is not mono-causal. On the one hand multifactorial studies with complex experimental design are required for its c...
Chris Bauer, Frank Kleinjung, Celia J. Smith, Mark...
BMCBI
2011
12 years 10 months ago
NeurphologyJ: an automatic neuronal morphology quantification method and its application in pharmacological discovery
Background: Automatic quantification of neuronal morphology from images of fluorescence microscopy plays an increasingly important role in high-content screenings. However, there ...
Shinn-Ying Ho, Chih-Yuan Chao, Hui-Ling Huang, Tza...
RECOMB
2011
Springer
12 years 9 months ago
Rich Parameterization Improves RNA Structure Prediction
Motivation. Current approaches to RNA structure prediction range from physics-based methods, which rely on thousands of experimentally-measured thermodynamic parameters, to machin...
Shay Zakov, Yoav Goldberg, Michael Elhadad, Michal...
SIGMOD
2011
ACM
210views Database» more  SIGMOD 2011»
12 years 9 months ago
A platform for scalable one-pass analytics using MapReduce
Today’s one-pass analytics applications tend to be data-intensive in nature and require the ability to process high volumes of data efficiently. MapReduce is a popular programm...
Boduo Li, Edward Mazur, Yanlei Diao, Andrew McGreg...