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» A framework for modelling virus gene expression data
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JCB
2007
198views more  JCB 2007»
15 years 4 months ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III
BMCBI
2006
147views more  BMCBI 2006»
15 years 4 months ago
A hidden Markov model approach for determining expression from genomic tiling micro arrays
Background: Genomic tiling micro arrays have great potential for identifying previously undiscovered coding as well as non-coding transcription. To-date, however, analyses of thes...
Kasper Munch, Paul P. Gardner, Peter Arctander, An...
BMCBI
2007
143views more  BMCBI 2007»
15 years 4 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
IJBRA
2006
59views more  IJBRA 2006»
15 years 4 months ago
Predicting altered pathways using extendable scaffolds
: Many diseases, especially solid tumors, involve the disruption or deregulation of cellular processes. Most current work using gene expression and other high-throughput data, simp...
B. M. Broom, T. J. McDonnell, D. Subramanian
BMCBI
2010
156views more  BMCBI 2010»
15 years 4 months ago
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison
Background: Candida albicans is a commonly encountered fungal pathogen in humans. The formation of biofilm is a major virulence factor in C. albicans pathogenesis and is related t...
Yu-Chao Wang, Chung-Yu Lan, Wen-Ping Hsieh, Luis A...