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BMCBI
2007
131views more  BMCBI 2007»
13 years 8 months ago
An improved method for identifying functionally linked proteins using phylogenetic profiles
Background: Phylogenetic profiles record the occurrence of homologs of genes across fully sequenced organisms. Proteins with similar profiles are typically components of protein c...
Shawn Cokus, Sayaka Mizutani, Matteo Pellegrini
BMCBI
2010
153views more  BMCBI 2010»
13 years 8 months ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
ICML
1994
IEEE
14 years 6 days ago
Hierarchical Self-Organization in Genetic programming
This paper presents an approach to automatic discovery of functions in Genetic Programming. The approach is based on discovery of useful building blocks by analyzing the evolution...
Justinian P. Rosca, Dana H. Ballard
BMCBI
2006
125views more  BMCBI 2006»
13 years 8 months ago
Automated functional classification of experimental and predicted protein structures
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
Kai Wang, Ram Samudrala
FPL
2004
Springer
109views Hardware» more  FPL 2004»
14 years 2 months ago
Hardware Accelerated Novel Protein Identification
The proteins in living organisms perform almost every significant function that governs life. A protein's functionality depends upon its physical structure, which depends on i...
Anish Alex, Jonathan Rose, Ruth Isserlin-Weinberge...