Background: Phylogenetic profiles record the occurrence of homologs of genes across fully sequenced organisms. Proteins with similar profiles are typically components of protein c...
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
This paper presents an approach to automatic discovery of functions in Genetic Programming. The approach is based on discovery of useful building blocks by analyzing the evolution...
Background: Proteins that are similar in sequence or structure may perform different functions in nature. In such cases, function cannot be inferred from sequence or structural si...
The proteins in living organisms perform almost every significant function that governs life. A protein's functionality depends upon its physical structure, which depends on i...
Anish Alex, Jonathan Rose, Ruth Isserlin-Weinberge...