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CEC
2009
IEEE
14 years 2 months ago
Evolutionary design of the energy function for protein structure prediction
— Automatic protein structure predictors use the notion of energy to guide the search towards good candidate structures. The energy functions used by the state-of-the-art predict...
Pawel Widera, Jonathan M. Garibaldi, Natalio Krasn...
CEC
2009
IEEE
14 years 3 days ago
A novel EDAs based method for HP model protein folding
— The protein structure prediction (PSP) problem is one of the most important problems in computational biology. This paper proposes a novel Estimation of Distribution Algorithms...
Benhui Chen, Long Li, Jinglu Hu
CEC
2005
IEEE
14 years 1 months ago
Evolving hidden Markov models for protein secondary structure prediction
New results are presented for the prediction of secondary structure information for protein sequences using Hidden Markov Models (HMMs) evolved using a Genetic Algorithm (GA). We a...
Kyoung-Jae Won, Thomas Hamelryck, Adam Prügel...
IJON
2010
199views more  IJON 2010»
13 years 4 months ago
DFS-generated pathways in GA crossover for protein structure prediction
Genetic Algorithms (GAs), as nondeterministic conformational search techniques, are promising for solving protein structure prediction (PSP) problems. The crossover operator of a ...
Tamjidul Hoque, Madhu Chetty, Andrew Lewis, Abdul ...
GECCO
2005
Springer
119views Optimization» more  GECCO 2005»
14 years 28 days ago
A multi-objective evolutionary approach to peptide structure redesign and stabilization
The prediction of the native structures of proteins, the socalled protein folding problem, is a NP hard multi-minima optimization problem for which to date no routine solutions ex...
Tim Hohm, Daniel Hoffmann