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» A graphical model for predicting protein molecular function
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BMCBI
2006
118views more  BMCBI 2006»
13 years 7 months ago
Predicting the effect of missense mutations on protein function: analysis with Bayesian networks
Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
Chris J. Needham, James R. Bradford, Andrew J. Bul...
BIOINFORMATICS
2007
151views more  BIOINFORMATICS 2007»
13 years 8 months ago
A new protein-protein docking scoring function based on interface residue properties
Motivation: Protein–protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low s...
Julie Bernauer, Jérôme Azé, Jo...
BMCBI
2007
97views more  BMCBI 2007»
13 years 8 months ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
BIOSYSTEMS
2007
109views more  BIOSYSTEMS 2007»
13 years 8 months ago
Protein folding and the robustness of cells
The intricate intracellular infrastructure of all known life forms is based on proteins. The folded shape of a protein determines both the protein’s function and the set of mole...
G. J. Shawn Tan, Ferran D. Revilla, Klaus-Peter Za...
AI
2005
Springer
13 years 7 months ago
Fast Protein Superfamily Classification Using Principal Component Null Space Analysis
Abstract. The protein family classification problem, which consists of determining the family memberships of given unknown protein sequences, is very important for a biologist for ...
Leon French, Alioune Ngom, Luis Rueda