Quantification of statistical significance is essential for the interpretation of protein structural similarity. To address this, a random model for protein structure comparison w...
Background: The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based com...
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
Abstract. Proteins, under native conditions, fold to specific 3D structures according to their 1D amino acid sequence, which in turn is defined by the genetic code. The specific...
Abstract. Over the last decade several prediction methods have been developed for determining structural and functional properties of individual protein residues using sequence and...
Huzefa Rangwala, Christopher Kauffman, George Kary...