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» A graphical model for predicting protein molecular function
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BMCBI
2004
114views more  BMCBI 2004»
13 years 7 months ago
HMM Logos for visualization of protein families
Background: Profile Hidden Markov Models (pHMMs) are a widely used tool for protein family research. Up to now, however, there exists no method to visualize all of their central a...
Benjamin Schuster-Böckler, Jörg Schultz,...
BMCBI
2007
141views more  BMCBI 2007»
13 years 8 months ago
Reconstruction of human protein interolog network using evolutionary conserved network
Background: The recent increase in the use of high-throughput two-hybrid analysis has generated large quantities of data on protein interactions. Specifically, the availability of...
Tao-Wei Huang, Chung-Yen Lin, Cheng-Yan Kao
BMCBI
2007
113views more  BMCBI 2007»
13 years 8 months ago
Hinge Atlas: relating protein sequence to sites of structural flexibility
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
Samuel Flores, Long J. Lu, Julie Yang, Nicholas Ca...
UAI
2004
13 years 9 months ago
Bayesian Learning in Undirected Graphical Models: Approximate MCMC Algorithms
Bayesian learning in undirected graphical models--computing posterior distributions over parameters and predictive quantities-is exceptionally difficult. We conjecture that for ge...
Iain Murray, Zoubin Ghahramani
CEC
2009
IEEE
14 years 17 days ago
A novel EDAs based method for HP model protein folding
— The protein structure prediction (PSP) problem is one of the most important problems in computational biology. This paper proposes a novel Estimation of Distribution Algorithms...
Benhui Chen, Long Li, Jinglu Hu