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    BMCBI
    2006
    122views more  BMCBI 2006»
    A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
    13 years 8 months ago
    A domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks
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    Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...
    Holger Conzelmann, Julio Saez-Rodriguez, Thomas Sa...
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    BMCBI
    2006
    108views more  BMCBI 2006»
    Gene function classification using Bayesian models with hierarchy-based priors
    13 years 8 months ago
    Gene function classification using Bayesian models with hierarchy-based priors
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    We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic ...
    Babak Shahbaba, Radford M. Neal
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    BMCBI
    2005
    109views more  BMCBI 2005»
    Automation of gene assignments to metabolic pathways using high-throughput expression data
    13 years 7 months ago
    Automation of gene assignments to metabolic pathways using high-throughput expression data
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    Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...
    Liviu Popescu, Golan Yona
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    ALMOB
    2006
    138views more  ALMOB 2006»
    A combinatorial optimization approach for diverse motif finding applications
    13 years 8 months ago
    A combinatorial optimization approach for diverse motif finding applications
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    Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
    Elena Zaslavsky, Mona Singh
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    BMCBI
    2008
    123views more  BMCBI 2008»
    A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
    13 years 8 months ago
    A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
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    Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
    Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
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