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» A graphical model for predicting protein molecular function
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NAR
2008
152views more  NAR 2008»
13 years 7 months ago
PROMALS3D web server for accurate multiple protein sequence and structure alignments
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Jimin Pei, Ming Tang, Nick V. Grishin
BMCBI
2010
174views more  BMCBI 2010»
13 years 8 months ago
The effect of prior assumptions over the weights in BayesPI with application to study protein-DNA interactions from ChIP-based h
Background: To further understand the implementation of hyperparameters re-estimation technique in Bayesian hierarchical model, we added two more prior assumptions over the weight...
Junbai Wang
ICASSP
2007
IEEE
14 years 2 months ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri
BMCBI
2011
13 years 2 months ago
ASPDock: protein-protein docking algorithm using atomic solvation parameters model
Background: Atomic Solvation Parameters (ASP) model has been proven to be a very successful method of calculating the binding free energy of protein complexes. This suggests that ...
Lin Li, Dachuan Guo, Yangyu Huang, Shiyong Liu, Yi...
BIOINFORMATICS
2011
13 years 2 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj