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» A graphical model for predicting protein molecular function
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NAR
2006
82views more  NAR 2006»
13 years 7 months ago
The RCSB PDB information portal for structural genomics
10 The RCSB Protein Data Bank (PDB) offers online tools, summary reports and target information related to the worldwide structural genomics initiatives from its portal at http://...
Andrei Kouranov, Lei Xie, Joanna de la Cruz, Li Ch...
GCB
2005
Springer
98views Biometrics» more  GCB 2005»
14 years 1 months ago
Composite Module Analyst: A Fitness-Based Tool for Prediction of Transcription Regulation
: Functionally related genes involved in the same molecular-genetic, biochemical, or physiological process are often regulated coordinately Such regulation is provided by precisely...
Alexander E. Kel, Tatiana Konovalova, Tagir Valeev...
BMCBI
2006
134views more  BMCBI 2006»
13 years 7 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...
CONSTRAINTS
2008
182views more  CONSTRAINTS 2008»
13 years 8 months ago
Constraint Programming in Structural Bioinformatics
Bioinformatics aims at applying computer science methods to the wealth of data collected in a variety of experiments in life sciences (e.g. cell and molecular biology, biochemistry...
Pedro Barahona, Ludwig Krippahl
BMCBI
2007
127views more  BMCBI 2007»
13 years 7 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...