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» A graphical model for protein secondary structure prediction
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JCC
2008
110views more  JCC 2008»
13 years 8 months ago
On the structure of the inverse kinematics map of a fragment of protein backbone
Loop closure in proteins requires computing the values of the inverse kinematics (IK) map for a backbone fragment with 2n 6 torsional degrees of freedom (dofs). It occurs in a va...
R. James Milgram, Guanfeng Liu, Jean-Claude Latomb...
CIBCB
2007
IEEE
13 years 12 months ago
Prediction of Enzyme Catalytic Sites from Sequence Using Neural Networks
The accurate prediction of enzyme catalytic sites remains an open problem in bioinformatics. Recently, several structure-based methods have become popular; however, few robust seq...
Swati Pande, Amar Raheja, Dennis R. Livesay
BIBE
2003
IEEE
124views Bioinformatics» more  BIBE 2003»
14 years 1 months ago
Prediction of Contact Maps Using Support Vector Machines
Contact map prediction is of great interest for its application in fold recognition and protein 3D structure determination. In this paper we present a contact-map prediction algor...
Ying Zhao, George Karypis
GECCO
2006
Springer
176views Optimization» more  GECCO 2006»
13 years 11 months ago
A genetic algorithm with backtracking for protein structure prediction
In this paper, we propose a simple genetic algorithm for finding the optimal conformation of a protein using the three-dimensional square HP model. A backtracking procedure is use...
Clayton Matthew Johnson, Anitha Katikireddy
SAC
2005
ACM
14 years 1 months ago
Graphical rule-based representation of signal-transduction networks
The process by which a cell senses and responds to its environment, as in signal transduction, is often mediated by a network of protein-protein interactions, in which proteins co...
James R. Faeder, Michael L. Blinov, William S. Hla...