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» A graphical model for protein secondary structure prediction
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GECCO
2005
Springer
119views Optimization» more  GECCO 2005»
14 years 2 months ago
A multi-objective evolutionary approach to peptide structure redesign and stabilization
The prediction of the native structures of proteins, the socalled protein folding problem, is a NP hard multi-minima optimization problem for which to date no routine solutions ex...
Tim Hohm, Daniel Hoffmann
EVOW
2004
Springer
14 years 27 days ago
Evolving Regular Expression-Based Sequence Classifiers for Protein Nuclear Localisation
A number of bioinformatics tools use regular expression (RE) matching to locate protein or DNA sequence motifs that have been discovered by researchers in the laboratory. For exam...
Amine Heddad, Markus Brameier, Robert M. MacCallum
JBCB
2010
138views more  JBCB 2010»
13 years 4 months ago
Hierarchical Classification of Gene Ontology Terms Using the Gostruct Method
Protein function prediction is an active area of research in bioinformatics. And yet, transfer of annotation on the basis of sequence or structural similarity remains widely used ...
Artem Sokolov, Asa Ben-Hur
BMCBI
2007
216views more  BMCBI 2007»
13 years 9 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos
RECOMB
2005
Springer
14 years 2 months ago
Probabilistic in Silico Prediction of Protein-Peptide Interactions
Abstract. Peptide recognition modules (PRMs) are specialised compact protein domains that mediate many important protein-protein interactions. They are responsible for the assembly...
Wolfgang P. Lehrach, Dirk Husmeier, Christopher K....