140 search results - page 26 / 28 » A hybrid genetic search for multiple sequence alignment |
BMCBI
2004
13 years 10 months ago
2004
Background: The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based com...
ICCAD
2009
IEEE
13 years 8 months ago
2009
IEEE
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
BMCBI
2005
13 years 10 months ago
2005
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
BMCBI
2010
13 years 11 months ago
2010
Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, an...
BMCBI
2006
13 years 11 months ago
2006
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...