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BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Identification of a small optimal subset of CpG sites as bio-markers from high-throughput DNA methylation profiles
Background: DNA methylation patterns have been shown to significantly correlate with different tissue types and disease states. High-throughput methylation arrays enable large-sca...
Hailong Meng, Edward Lenn Murrelle, Guoya Li
CORR
2011
Springer
201views Education» more  CORR 2011»
12 years 11 months ago
On the Weakenesses of Correlation
The correlation of the result lists provided by search engines is fundamental and it has deep and multidisciplinary ramifications. Here, we present automatic and unsupervised met...
Paolo D'Alberto, Ali Dasdan
BMCBI
2007
120views more  BMCBI 2007»
13 years 7 months ago
Re-sampling strategy to improve the estimation of number of null hypotheses in FDR control under strong correlation structures
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
Xin Lu, David L. Perkins
BMCBI
2010
100views more  BMCBI 2010»
13 years 7 months ago
Efficiency clustering for low-density microarrays and its application to QPCR
Background: Pathway-targeted or low-density arrays are used more and more frequently in biomedical research, particularly those arrays that are based on quantitative real-time PCR...
Eric F. Lock, Ryan Ziemiecki, J. S. Marron, Dirk P...
ICIP
1998
IEEE
13 years 11 months ago
Spatially Adaptive Wavelet Thresholding with Context Modeling for Image Denoising
The method of wavelet thresholding for removing noise, or denoising, has been researched extensively due to its effectiveness and simplicity. Much of the literature has focused on ...
S. Grace Chang, Bin Yu, Martin Vetterli