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BMCBI
2006
118views more  BMCBI 2006»
13 years 9 months ago
Statistical analysis of an RNA titration series evaluates microarray precision and sensitivity on a whole-array basis
Background: Concerns are often raised about the accuracy of microarray technologies and the degree of cross-platform agreement, but there are yet no methods which can unambiguousl...
Andrew J. Holloway, Alicia Oshlack, Dileepa S. Diy...
BMCBI
2007
182views more  BMCBI 2007»
13 years 9 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
BIBM
2010
IEEE
157views Bioinformatics» more  BIBM 2010»
13 years 7 months ago
Decomposing PPI networks for complex discovery
Abstract--Protein complexes are important for understanding principles of cellular organization and functions. With the availability of large amounts of high-throughput proteinprot...
Guimei Liu, Chern Han Yong, Limsoon Wong, Hon Nian...
DIS
2005
Springer
14 years 3 months ago
The Arrowsmith Project: 2005 Status Report
In the 1980s, Don Swanson proposed the concept of “undiscovered public knowledge,” and published several examples in which two disparate literatures (i.e., sets of articles hav...
Neil R. Smalheiser
EDBT
2009
ACM
277views Database» more  EDBT 2009»
14 years 2 months ago
G-hash: towards fast kernel-based similarity search in large graph databases
Structured data including sets, sequences, trees and graphs, pose significant challenges to fundamental aspects of data management such as efficient storage, indexing, and simila...
Xiaohong Wang, Aaron M. Smalter, Jun Huan, Gerald ...