139 search results - page 5 / 28 » A multi-expert system for the automatic detection of protein... |
BMCBI
2010
13 years 2 months ago
2010
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
BMCBI
2008
2008
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
13 years 7 months ago
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
BMCBI
2010
13 years 7 months ago
2010
Background: An important problem in genomics is the automatic inference of groups of homologous proteins from pairwise sequence similarities. Several approaches have been proposed...
BMCBI
2005
13 years 7 months ago
2005
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
BMCBI
2004
13 years 7 months ago
2004
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...