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BMCBI
2010
98views more  BMCBI 2010»
13 years 11 months ago
A semi-nonparametric mixture model for selecting functionally consistent proteins
Background: High-throughput technologies have led to a new era of proteomics. Although protein microarray experiments are becoming more common place there are a variety of experim...
Lianbo Yu, R. W. Doerge
BMCBI
2010
139views more  BMCBI 2010»
13 years 11 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
MICRO
2008
IEEE
146views Hardware» more  MICRO 2008»
13 years 11 months ago
A small cache of large ranges: Hardware methods for efficiently searching, storing, and updating big dataflow tags
Dynamically tracking the flow of data within a microprocessor creates many new opportunities to detect and track malicious or erroneous behavior, but these schemes all rely on the...
Mohit Tiwari, Banit Agrawal, Shashidhar Mysore, Jo...
BMCBI
2004
208views more  BMCBI 2004»
13 years 10 months ago
Hybrid clustering for microarray image analysis combining intensity and shape features
Background: Image analysis is the first crucial step to obtain reliable results from microarray experiments. First, areas in the image belonging to single spots have to be identif...
Jörg Rahnenführer, Daniel Bozinov
BMCBI
2008
139views more  BMCBI 2008»
13 years 11 months ago
A topological transformation in evolutionary tree search methods based on maximum likelihood combining p-ECR and neighbor joinin
Background: Inference of evolutionary trees using the maximum likelihood principle is NP-hard. Therefore, all practical methods rely on heuristics. The topological transformations...
Maozu Guo, Jian-Fu Li, Yang Liu