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» A new approach to fragment assembly in DNA sequencing
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FOCS
1995
IEEE
13 years 11 months ago
Reconstructing Strings from Substrings in Rounds
We establish a variety of combinatorial bounds on the tradeo s inherent in reconstructing strings using few rounds of a given number of substring queries per round. These results ...
Dimitris Margaritis, Steven Skiena
APBC
2004
13 years 8 months ago
Mega Weaver: A Simple Iterative Approach for BAC Consensus Assembly
Hierarchical genome assembly can be divided into three distinct stages: sequencing and assembling shotgun reads for each of a series of selected BAC clones; assembling the resulti...
Daolong Wang, Mario Lauria, Bo Yuan, Fred A. Wrigh...
JCB
2000
105views more  JCB 2000»
13 years 7 months ago
A Greedy Algorithm for Aligning DNA Sequences
For aligning DNA sequences that differ only by sequencing errors, or by equivalent errors from other sources, a greedy algorithm can be much faster than traditional dynamic progra...
Zheng Zhang 0004, Scott Schwartz, Lukas Wagner, We...
BMCBI
2010
133views more  BMCBI 2010»
13 years 7 months ago
Improving de novo sequence assembly using machine learning and comparative genomics for overlap correction
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
Lance E. Palmer, Mathäus Dejori, Randall A. B...
CORR
2007
Springer
81views Education» more  CORR 2007»
13 years 7 months ago
Faster exon assembly by sparse spliced alignment
Assembling a gene from candidate exons is an important problem in computational biology. Among the most successful approaches to this problem is spliced alignment, proposed by Gelf...
Alexandre Tiskin