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» A new approach to nonrepetitive sequences
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BMCBI
2005
100views more  BMCBI 2005»
13 years 10 months ago
EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Jean-Christophe Gelly, Laurent Chiche, Jér&...
BMCBI
2005
132views more  BMCBI 2005»
13 years 10 months ago
CLPM: A Cross-Linked Peptide Mapping Algorithm for Mass Spectrometric Analysis
Background: Protein-protein, protein-DNA and protein-RNA interactions are of central importance in biological systems. Quadrapole Time-of-flight (Q-TOF) mass spectrometry is a sen...
Yong Tang, Yingfeng Chen, Cheryl F. Lichti, Roger ...
TKDE
2008
127views more  TKDE 2008»
13 years 10 months ago
Maximal Subspace Coregulated Gene Clustering
Clustering is a popular technique for analyzing microarray data sets, with n genes and m experimental conditions. As explored by biologists, there is a real need to identify coregu...
Yuhai Zhao, Jeffrey Xu Yu, Guoren Wang, Lei Chen 0...
RECOMB
2006
Springer
14 years 10 months ago
A Study of Accessible Motifs and RNA Folding Complexity
mRNA molecules are folded in the cells and therefore many of their substrings may actually be inaccessible to protein and microRNA binding. The need to apply an accessability crite...
Ydo Wexler, Chaya Ben-Zaken Zilberstein, Michal Zi...
KDD
2001
ACM
192views Data Mining» more  KDD 2001»
14 years 10 months ago
Data mining with sparse grids using simplicial basis functions
Recently we presented a new approach [18] to the classification problem arising in data mining. It is based on the regularization network approach but, in contrast to other method...
Jochen Garcke, Michael Griebel