322 search results - page 15 / 65 » A new approach to sequence comparison: normalized sequence a... |
BMCBI
2010
13 years 7 months ago
2010
Background: With the continued development of new computational tools for multiple sequence alignment, it is necessary today to develop benchmarks that aid the selection of the mo...
BMCBI
2007
13 years 7 months ago
2007
Background: Sequence comparison faces new challenges today, with many complete genomes and large libraries of transcripts known. Gene annotation pipelines match these sequences in...
EVOW
2010
Springer
13 years 10 months ago
2010
Springer
A challenging problem in bioinformatics is the detection of residues that account for protein function specificity, not only in order to gain deeper insight in the nature of functi...
BMCBI
2004
13 years 7 months ago
2004
Background: The prediction of ancestral protein sequences from multiple sequence alignments is useful for many bioinformatics analyses. Predicting ancestral sequences is not a sim...
TCBB
2010
13 years 5 months ago
2010
— We describe a theoretical unifying framework to express comparison of RNA structures, which we call alignment hierarchy. This framework relies on the definition of common supe...