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    BMCBI
    2011
    242views Artificial Intelligence» more  BMCBI 2011»
    Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in i
    13 years 2 months ago
    Statistical Test of Expression Pattern (STEPath): a new strategy to integrate gene expression data with genomic information in i
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    Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
    Paolo G. V. Martini, Davide Risso, Gabriele Sales,...
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    BMCBI
    2007
    86views more  BMCBI 2007»
    Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
    13 years 7 months ago
    Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of
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    Background: Deficiencies in microarray technology cause unwanted variation in the hybridization signal, obscuring the true measurements of intracellular transcript levels. Here we...
    William O. Ward, Carol D. Swartz, Steffen Porwolli...
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    BMCBI
    2006
    125views more  BMCBI 2006»
    Evaluating different methods of microarray data normalization
    13 years 7 months ago
    Evaluating different methods of microarray data normalization
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    Background: With the development of DNA hybridization microarray technologies, nowadays it is possible to simultaneously assess the expression levels of thousands to tens of thous...
    André Fujita, João Ricardo Sato, Leo...
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    BMCBI
    2011
    189views Artificial Intelligence» more  BMCBI 2011»
    Support vector machines-based identification of alternative splicing in Arabidopsis thaliana from whole-genome tiling arrays
    13 years 2 months ago
    Support vector machines-based identification of alternative splicing in Arabidopsis thaliana from whole-genome tiling arrays
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    Background: Alternative splicing (AS) is a process which generates several distinct mRNA isoforms from the same gene by splicing different portions out of the precursor transcript...
    Johannes Eichner, Georg Zeller, Sascha Laubinger, ...
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    BIOINFORMATICS
    2005
    72views more  BIOINFORMATICS 2005»
    Use of within-array replicate spots for assessing differential expression in microarray experiments
    13 years 7 months ago
    Use of within-array replicate spots for assessing differential expression in microarray experiments
    Download  www.statsci.org
    Motivation. Spotted arrays are often printed with probes in duplicate or triplicate, but current methods for assessing differential expression are not able to make full use of the...
    Gordon K. Smyth, Joëlle Michaud, Hamish S. Sc...
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