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» A parameter-less genetic algorithm
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BMCBI
2007
166views more  BMCBI 2007»
13 years 10 months ago
Optimization of filtering criterion for SEQUEST database searching to improve proteome coverage in shotgun proteomics
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Xinning Jiang, Xiaogang Jiang, Guanghui Han, Mingl...
GPEM
2008
98views more  GPEM 2008»
13 years 10 months ago
Sporadic model building for efficiency enhancement of the hierarchical BOA
Efficiency enhancement techniques--such as parallelization and hybridization--are among the most important ingredients of practical applications of genetic and evolutionary algori...
Martin Pelikan, Kumara Sastry, David E. Goldberg
ML
2008
ACM
101views Machine Learning» more  ML 2008»
13 years 9 months ago
On reoptimizing multi-class classifiers
Significant changes in the instance distribution or associated cost function of a learning problem require one to reoptimize a previously-learned classifier to work under new cond...
Chris Bourke, Kun Deng, Stephen D. Scott, Robert E...
TCBB
2008
115views more  TCBB 2008»
13 years 9 months ago
Highly Scalable Genotype Phasing by Entropy Minimization
A Single Nucleotide Polymorphism (SNP) is a position in the genome at which two or more of the possible four nucleotides occur in a large percentage of the population. SNPs accoun...
Alexander Gusev, Ion I. Mandoiu, Bogdan Pasaniuc
BMCBI
2005
67views more  BMCBI 2005»
13 years 9 months ago
Selecting additional tag SNPs for tolerating missing data in genotyping
Background: Recent studies have shown that the patterns of linkage disequilibrium observed in human populations have a block-like structure, and a small subset of SNPs (called tag...
Yao-Ting Huang, Kui Zhang, Ting Chen, Kun-Mao Chao